2011年1月4日火曜日

tuberculous meningitis

そして来週いきなりケースカンファを当てられてしまった!
結核性髄膜炎

今日のヘエーは
tuberculous meningitis 診断について
2010年の論文でも 診断基準がないことが問題視されていて
ようやくその基準をつくるためのスタディーをするための診断基準が
決まりました 的なレベル。

そんな中で見つけたのは


1、7日より長い前駆症状
2、眼底検査での視神経萎縮
3、局所神経症状
4、不随意運動(とくに小児)
5、髄液多核球が50%以下

1つでもあれば感度がとても高く、3つ以上あれば特異度がとても高い

Kumar R, Singh SN, Kohli N : A diagnostic rule for
tuberculous meningitis. Arch Dis Child 1999 ; 81 :
221224.

で述べられているのは小児の話だが1項目なら 感度98.4%
3項目なら特異度 98.3%と書いてある。

1 件のコメント:

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